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Home » Radio Archive » Daily Show » Immune Microparticles

Immune Microparticles

July 28, 2009
https://podcast.scienceupdate.com/090728_sciup_immu.mp3

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BOB HIRSHON (host):
Smarter immune therapy. I’m Bob Hirshon and this is Science Update.

Organ transplant patients take broad-acting drugs that cripple their entire immune system, in order to protect the new organ. But in the future, a more targeted therapy lasting just a few weeks may do the trick. Anatolij Horuska and his colleagues at the Medical College of Georgia are working with a natural molecule called HLA-G. Fetuses use it to make peace with Mom’s immune system. It acts on dendritic cells, a kind of immune cell that identifies new threats and rallies the rest of the immune system against them.

ANATOLIJ HORUSKA (Medical College of Georgia):
So if we target this early stage of recognition, we will create tolerance mechanisms.

HIRSHON:
Horuska’s strategy is to deliver the molecule in microscopic, degradable beads, which are injected right after a transplant. Recent trials in mice with skin grafts look promising. I’m Bob Hirshon for AAAS, the Science Society.

Category: Daily ShowTag: Medicine & Health, Microbiology
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